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BioMarck Pharmaceuticals, Ltd. is a privately owned biopharmaceutical company founded in 2002 by Mr. Allen F. Gant, founding chairman and CEO, Mr. Thomas Roberg, current chairman, and Dr. Indu Parikh, founding and current President & CSO. BioMarck is dedicated to the discovery and development of new drugs for the treatment of pulmonary diseases and disorders associated with the over-secretion of mucus and pulmonary inflammation. In developing its lead compound, BIO-11006 Inhalation Solution, BioMarck has chosen chronic obstructive pulmonary disease (COPD) as its first target, but other diseases including asthma, and cystic fibrosis are later disease targets. BIO-11006 Inhalation Solution works by a novel dual mechanism based on MARCKS protein; BIO-11006 inhibits both the secretion of mucus in the lungs and pulmonary inflammation, which are hallmarks of various lung diseases. BioMarck has completed a full panel of preclinical safety studies, has an active IND with the FDA, has completed two Phase 1 clinical studies, and a Phase 2a study of the efficacy of BIO-11006 in COPD patients that demonstrated proof-of-concept of its novel COPD therapeutic. In the ensuing years other important functions of MARCKS protein have been discovered and large library of peptide inhibitors of MARCKS protein have been identified, synthesized, and patented. The Company has grown from a single investigational product and single indication company to a company with a platform technology with multiple investigational products and multiple indications including ARDS, lung, and breast cancer. BioMarck licensed its technology on a worldwide exclusive basis from North Carolina State University, based on the work of Kenneth B. Adler, Ph.D., Professor of Cell Biology.

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