SELECTIVE ANTI-MARCKS TECHNOLOGIES

biomarck is developing technology that utilizes targeted anti-Marcks technology for the treatment of Cancer and Acute Respiratory Distress Syndrome (ARDS)

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The Discovery

Utilizing targeted anti-Marcks peptides in order to develop and license products targeted at difficult to treat diseases with unmet needs.

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Publications

Cancer_pub_new

Cancer

1.Anti-MARCKS Peptides Inhibit Lung Cancer Metastasis in Mice

2.Inhibition of Lung Cancer Metastasis in mice by inhaled aerosolized anti-MARCKS peptides

3.MicroRNA-21 (miR-21) Affects Migration of Human Lung Cancer Cells in vitro via Regulation of MARCKS Expression

4.MARCKS Protein Inhibitors Attenuate Cancer Cell Migration/Metastasis

5.Regulated mucin secretion from airway epithelial cells

6.A Novel Predictor of Cancer Malignancy: Up-regulation of Myristoylated Alanine-Rich C Kinase Substrate Phosphorylation in Lung Cancer

ARDS_pub_1

ARDS

1.Anti-MARCKS Peptides Reverse LPS-induced Acute Respiratory Distress Syndrome (ARDS) in Mice

2.A peptide that inhibits function of Myristoylated Alanine-Rich
C Kinase Substrate (MARCKS) reduces lung cancer metastasis

COPD_pub_new

COPD

1.Enhanced Expression of Myristoylated Alanine – Rich C Kinase Substrate (MARCKS) in Airway Epithelium of an Animal Model of Allergic Airway Inflammation and Human Patients with COPD

2.An Inhaled Inhibitor of Myristoylated Alanine-Rich C Kinase Substrate
Reverses LPS-Induced Acute Lung Injury in Mice

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For Children

biomarck pharmaceuticals intends to support children with difficult to treat cancers such as Rhabdomyosarcoma and Neuroblastoma. This may be done by a compassionate use program under the Investigator IND of the treating hospital. This effort will be done in support of the concepts of non-profit organizations such as the Miami based Live Like Bella Foundation (Learn More) which supports children with cancer, their families and research into childhood cancer.

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INVESTORS

Letter to Biomarck Investors

Biomarck Overview

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